In the table below, the amino acid sequences of the multiple sclerosis autoantigens, myelin basic protein (MBP) , myelin oligodendrocyte glycoprotein (MOG) and claudin 11 are shown in the dark grey columns and vatches in the light grey columns, where the aligning viral and phage sequences can be compared with the autoantigen amino acid sequence. The gaps in the vatches represent non-homologous amino acids, and the + sign represents an unspecified amino acid with similar properties to that of the autoantigen amino acid. The red background in the B cell and T cell antigenicity columns represent B cell indices above 0.35 and T cell indices above 0.5 (the server set threshold for epitope prediction).

Red viruses are known to infect humans: Blue viruses are from farm animals, (chickens, turkeys, cattle , sheep and horses etc) dogs, cats, mice, bats, flies and insects etc, or human food , (e.g. salmon and oyster viruses). Green viruses are plant or more exotic viruses. Animal, plant or exotic viruses may or may not cause human disease, but can enter tissues via cuts, inhalation or ingestion.

 

AA MBP MBP Viral vatches B cell MBP T cell MBP AA MOG MOG Viral vatches B cell MOG T cell MOG AA Cldn Claudin viral vatches B cell Claudin T cell claudin
M Enterobacteria phage MASQK 0.66 0.72 M M -0.37 0.70 M M -1.08 0.43  
A A 0.85 0.50 A A -0.10 0.72 V V -1.42 0.66  
S S 0.93 0.04 S S 0.04 0.06 A A -1.33 0.16  
Q Asian prunis virus QRHGSK 1.08 0.24 L L 0.34 0.97 T T -1.36 0.04  
K Staphylococcus phage KRPSQ 1.19 0.95 S hepatitis C S PSLPSCL 0.28 0.04 C C -1.37 0.03  
R R 1.43 0.16 R Fowlpox RPSLPS L Porcine teschovirus RPSLP Psittacid herpesvirus 1 RP  PSC CS  LLL
0.44 0.10 L Ostreococcus tauri virus   L+VVG  +VTS        +TTS N Tomato leaf curl New Delhi virus  L+   FVTS+V -1.21 0.61  
P HHV-7 PSQRHGS 1.51 0.04 P P 0.57 0.04 Q Clostridium phage  +VGFV SF+ -1.32 0.02  
S S 1.53 0.03 S S 0.45 0.02 V Synechococcus phage VVGF    +G IG+   TS  DW -1.29 0.34  
Q Cherry necrotic rusty mottle virus +R+  KYLA 1.53 0.05 L L 0.31 0.91 V Epstein-Barr V FV  FVGW Bombyx mori cypovirus V FVTSFV
-1.25 0.14  
R Orange-spotted grouper iridovirus RHGS YL Turbot reddish body iridovirus  RHGS YL 1.39 0.47 P P -0.10 0.03 G G -1.15 0.03  
H H 1.09 0.37 S S -0.35 0.56 F Fiji disease virus FVT F+GW -1.02 0.25  
G G 0.67 0.03 C C -0.87 0.03 V V -1.06 0.06  
S Deerpox virus SKY A AST 0.40 0.04 L L -1.57 0.97 T T -0.87 0.11  
K K 0.27 0.96 C C -2.05 0.13 S  Synechococcus phage SF GW       G   TTST DW and  SFV WIG
-0.93 0.09  
Y Y 0.23 0.84 S S -2.60 0.03 F F -1.10 0.86  
L L 0.28 0.93 F Swinepox FLLLLL -3.16 0.83 V Swine fever virus +GW GVI -0.83 0.09  
A A 0.27 0.75 L L -3.53 0.86 G Klebsiella phage GWIGV
 Cycas necrotic stunt virus GW  V  TTST
-0.96 0.04  
T Rice gall dwarf virus TASTMD 0.01 0.08 L Infectious salmon anemia virus LLLLLQV -3.57 0.48 W Human parvovirus 4 WI V  I     TTSTN  DW Adeno-associated virus W G  VI TTST  W        PTC Varicella WI  +V TST -1.20 0.52  
A A 0.10 0.31 L L -3.36 0.70 I Dengue virus IGVI+T human herpesvirus 6 IG   IVTTS -1.41 0.05  
S S 0.19 0.03 L L -3.39 0.69 G Duck enteritis virus GVIVTT T Tensaw virus  G IVTTST +
-1.12 0.03  
T T 0.45 0.16 L Feline coronavirus  LLQV Ovine enzootic nasal tumor virus LLQ  SS A  F  I  RHPI
  
-2.80 0.38 V Prochlorococcus phage V +TTSTN  Helicobasidium mompa endornavirus V VTT   DWVV
-0.88 0.30  
M Glossina pallidipes salivary gland hypertrophy virus  M  ARHG   R RDT 0.56 0.93 L Synechococcus phage LQ SSS+AG -2.25 0.89 I HIV-1 IVT STND Lactobacillus phage  IV  STN W+V Chapare virus IV TST Bunyamwera virus IVTTST +
 Human rhinovirus IVTTS

-0.69 0.63  
D D 0.47 0.44 Q Q -1.59 0.05 V Dengue virus V T TNDW  VVT Aeromonas phage  VT STND W HIV-1 VT STND
-0.27 0.74  
H H 0.39 0.47 V Bat coronavirus V SSYA     +  VIGPR -1.06 0.89 T Human parvovirus 4 TTSTN  DW 0.14 0.20  
A Marseillevirus AR GFLP 0.07 0.06 S S -0.49 0.05 T T 0.35 0.24  
R Klebsiella phage RHG+  RHR TG -0.24 0.19 S S 0.05 0.08 S Oliveros virus S N  VV     IP   KLDELG   SK
Ostreococcus tauri virus STN W   VVT
0.33 0.03  
H H -0.14 0.18 S S 0.58 0.13 T Serra do Navio virus TN W  TCG Y 0.46 0.06  
G G -0.24 0.04 Y Synechococcus phage  Y GQF VI 0.36 0.97 N Norwalk virus Norovirus Chiba virus Southampton virus NDWVV CG  Apple mosaic virus NDW           V TCGYT Lactococcus phage  NDW  TCG
0.42 0.03  
F F -0.10 0.85 A Shigella phage AGQF V G Norwalk virus AGQF VI P 0.42 0.36 D D 0.36 0.04  
L L -0.02 0.77 G G 0.06 0.08 W  NDW  TCG 0.18 0.88  
P P 0.15 0.03 Q Q -0.20 0.03 V V 0.06 0.15  
R Shrimp white spot syndrome virus R+ GILDS 0.27 0.79 F Rhodococcus phage FRVIGP -0.22 0.61 V V -0.27 0.57  
H Synechococcus phage+RD GIL 0.35 0.83 R Psittacid herpesvirus 1 RVIGP     ALVGD Dengue virus RVI PR
 Measles R IGPR+  +  L GD  E ELP and R IGPR+  and RV+GPR+  +  L  D  E ELP
-0.13 0.14 T T -0.31 0.11  
R Synechococcus phage RDT ILD 0.34 0.28 V Infectious bronchitis virus V+GPRH Feline coronavirus and Bat coronavirus VI PRH I 0.10 0.88 C Human herpesvirus 6 C + I TCR L -0.64 0.11  
D Rubella DT I D I RFFG Acinetobacter phage D GILD + Foot and mouth virus DTG  ILD 0.31 0.07 I I 0.15 0.76 G G -0.36 0.03  
T Deftia phageTGI DSIG  FG  Enterococcus phage TG  D I R FFGG Aphid lethal paralysis virus TGI++    FFG
0.39 0.05 G G 0.08 0.03 Y Influenza A |+TI   R   EL SKGLW and YTI   R   E+ S GLW
-0.16 0.95  
G Fowl adenovirus 4 GIL+ I R+ 0.40 0.05 P Human Coronavirus PRH  R L 0.18 0.03 T Human rhinovirus TIPTC  0.13 0.02  
I HSV-2 IL D  GRF G D  APKR 0.11 0.36 R R 0.31 0.22 I Measles IP  RKL ELG Human rhinovirus IPTC             +C  AT  Y CK      P VDI 0.08 0.46  
L Enterobacteria, Salmonella and yersinia phages LDSIGRF Enterobacteria phage LD IGRF
 Mycobacterium phage LDSIGA Acanthamoeba polyphaga mimivirus LDSIGR


0.08 0.85 H Wesselsbron virus H IR LVG+E 0.38 0.03 P P 0.14 0.08  
D Helicobasidium mompa endornavirus DSIGRF Papaya ringspot virus  D IGR+FG Acanthamoeba polyphaga mimivirus +SI  FFGG+
Turnip  mosaic virus DSI RFF  GD
-0.22 0.05 P Lactobacillus phage PI ALVG++ Synechococcus phage PI   LVG+EVE 0.24 0.07 T Sleeping disease virus and Norwegian salmonid alphavirus TCR LD+L   G -0.17 0.36  
S Sandfly Sicilian Turkey virus SIGRFF Wongabel virus SIG FFGG
-0.57 0.19 I Synechococcus phage I ALVG E VELand  IRALVG   VEL Prochlorococcus phage IRALVG   VEL Tamana bat virus IRAL+GD -0.01 0.86 C C 0.10 0.03  
I Acanthamoeba polyphaga mimivirus IGRFFGG Porcine reproductive and respiratory syndrome virus IGR  GG R  Granada virus IGRFF  D Toscana virus IGRFF  D
-0.90 0.45 R R 0.00 0.77 R Acanthocystis turfacea Chlorella virus 1 RKLDEL        KG WA 0.04 0.79  
G Meleagrid herpesvirus 1 GRFFGG HSV-2 GRF G D  APKR -0.58 0.03 A A -0.08 0.16 K Oliveros virus  KLDELG   SK  Amapari virus Allpahuayo virus Chapare virus Cupixi virus Junin virus Latinovirus Machupo virus Paranavirus Sabia virus Tacaribe virus KLDELG Cassava brown streak virus KL+ELG Hexaprotodon liberiensis gammaherpesvirus RKL+EL

0.00 0.97  
R Bacillus phage  RFFG +R -0.20 0.49 L Synechococcus and Prochlorococcus phage  LVGD+V Measles L GD  E ELP Human astrovirus  +VGD+VE
-0.01 0.97 L L 0.09 0.96  
F Norwalk and norovirus FFGGD Lactobacillus phage  FFGG Microplitis demolitor bracovirus FFGGDR
0.06 0.97 V Shigella phage VG  VEL   + P  NAT   V WY -0.15 0.94 D D 0.17 0.02  
F F 0.16 0.79 G HIV-1 G+ + LPCRI  0.19 0.09 E Influenza a EL S GLW 0.26 0.04  
G HIV-1 GGDRG Burkholderia phage GGDR GA KR
0.59 0.03 D D -0.14 0.08 L L 0.42 0.24  
G Peste-des-petits-ruminants virus  G+RG PKR 0.70 0.05 E E 0.01 0.02 G G 0.21 0.03  
D Peste-des-petits-ruminants virus +RGAPKR 0.93 0.12 V Cytomegalovirus VEL CR S G N HIV-1 +ELPCRI Human Coronavirus VEL  PCR 0.21 0.95 S S 0.25 0.03  
R Human adenovirus 4  RG  K+PWLK  1.42 0.34 E E 0.38 0.03 K K 0.03 0.56  
G Pseudomonas phage GAP  GSGK P Listeria phage GAP RG 1.89 0.48 L L 0.08 0.97 G G 0.04 0.08  
A A 1.97 0.23 P Wesselsbron virus PCRI Human herpsvirus 6 PC IS   NA    VGW+ 0.07 0.04 L Bovine viral diarrhea virus LWAD 0.09 0.69  
P P 2.02 0.03 C C -0.01 0.05 W W -0.25 0.51  
K Cocal virus KRGSGK  W Trichoplusia ni ascovirus KRGSG 1.86 0.50 R Pseudomonas Phage RISP KN  0.39 0.05 A Wheat eqlid mosaic virus A CVMATG -0.65 0.13  
R HMO Astrovirus A RG PKRG G   W Enterobacteria phage  RGS GK  W KPGR Human adenovirus 4 RG  K+PWLK Zika virus  RGS K+ WL
 
1.91 0.53 I I 0.47 0.84 D Swine fever virus DCV  M     LYHCK -0.82 0.03  
G Fowl adenovirus 4 GSGK 1.65 0.04 S Synechococcus and Prochlorococcus phage SPGKN 0.96 0.02 C C -0.88 0.02  
S S 1.54 0.03 P P 1.03 0.03 V Ostreid herpesvirus 1 VMAT LY -0.58 0.13  
G Visna Maedi virus GK+PW L PGR Listeria phage G VPW K 1.16 0.03 G G 1.23 0.19 M Staphylococcus phage MATGLY  Sonchus yellow net virus M  G YHCK
-0.65 0.50  
K K 0.86 0.67 K Lymphocystis disease virus  KNAT 1.31 0.92 A Serra do Navio virus ATGL -0.74 0.66  
V Rice stripe virus VPW+K GRS 0.80 0.92 N Human coxsackievirus  NATGM 1.39 0.03 T Acute bee paralysis virus TG    LYHC    DIL L -1.00 0.04  
P Torque teno PWL PGR SP 0.72 0.04 A A 1.34 0.08 G G -0.88 0.04  
W Torque teno virus WL PGRS 0.76 0.97 T Influenza a  TGM  GWYR and TGM  GWY 1.08 0.04 L L -0.61 0.36  
L HSV-2 LKPGR GB virus  L PGR PLP Wood mouse herpesvirus Apodemus flavicollis rhadinovirus L PGRSP
0.92 0.91 G Streptococcus pyogenes phage G  VGW RPP+S Influenza a GM  GWY 0.91 0.20 Y Salmonella phage YHCKPL D Turkey coronavirus Y CKP   ILIL Infectious bronchitis virus Y CKP   ILIL
-0.41 0.64  
K Influenza A K GRSPLPS Physalis mottle virus  KPGR  LP H
0.90 0.86 M M 0.39 0.96 H H -0.56 0.05  
P Equid herpesvirus 9 P R  LPS+AR 1.06 0.24 E Small ruminant lentivirus EY GRT   K+ I 0.23 0.03 C Epstein-Barr CK LVD+L -0.70 0.03  
G Prochlorococcus phage GRSPLP 0.99 0.28 V Lettuce infectious yellows virus V WYR 0.37 0.52 K K -0.78 0.55  
R R 1.36 0.36 G Synechococcus and Prochlorococcus phage GWYR 0.40 0.03 P Cassava brownstreak virus PLVDIL+ Rice stripe necrosis virus P VDIL PL+DILI Deerpox virus LVDI  IL   nnn     A  LMIAA  LG -0.88 0.04  
S S 1.60 0.24 W Equine coronavirus WY PPF 0.45 0.83 L African swine fever LVDILI Bovine viral diarrhea virus  LV  LILP Y Alcelaphine herpesvirus  LVDI  IL  -1.11 0.12  
P P 1.56 0.03 Y Y 0.53 0.24 V Hepatitis c VD   L GY  ACR L+ Lymphocystis disease virus  VDILI LP Y VQ  Lymphocystis disease virus  VDILI LP Y VQ -1.27 0.42  
L Zika virus LPSH 1.48 0.96 R R 0.52 0.05 D Meleagrid herpesvirus  D +IL  GYVQAC -1.53 0.05  
P P 1.31 0.11 P Cherry rasp leaf virus PPF   VHLY Human rotavirus PPFS    R V LY
0.59 0.04 I bovine viral diarrhea virus strain Oregon ILILP Y Swine fever virus  ILILP Y
-1.55 0.24  
S Maize dwarf mosaic virus SHA S  G CNM 1.22 0.48 P P 0.29 0.03 L Adeno-associated virus L+LPGY -1.38 0.13  
H H 1.28 0.49 F Torque teno sus virus F  VV LY   KDQD Equid herpesvirus 9 FSR V    NG D DGD Q  Streptococcus phage FSRV  Pipistrellus bat and Bat coronavirus F RVV LY
0.27 0.38 I West Nile virus IL  PGY -1.16 0.13  
A Hepatitis B AR  PGLC  Y DS 1.24 0.96 S S 0.08 0.02 L L -1.14 0.88  
R Human rotavirus  RSQ  LC  Y +   Tuber aestivum virus RSQPGL
1.41 0.86 R R -0.52 0.28 P P -1.15 0.05  
S S 1.05 0.73 V Infectious bronchitis virus VV L RNGK -0.81 0.89 G Meleagrid herpesvirus 1 GYVQAC Ictalurid herpesvirus 1 G+ +ACRAL   A V
-0.89 0.04  
Q Dysaphis plantaginea densovirus QPGLC M  Campylobacter phage  QPGLC M+K  Aeromonas phage Q GLC 0.76 0.04 V V -0.98 0.97 Y Bluetongue virus YV     LMIAAS  Cytomegalovirus Y Q CRALM  Aeromonas phage Y QACR L Turkey coronavirus Infectious bronchitis virus Y QACRA
-0.51 0.55  
P Acanthamoeba polyphaga mimivirus P LCNMY  0.57 0.07 H H -0.79 0.44 V Hantavirus Seoulvirus +Q C ALMIA  -0.26 0.77  
G Banna virus GL NMY KD H 0.32 0.04 L Porcine lymphotropic herpesvirus  LYRNGK -0.74 0.98 Q Q -0.19 0.23  
L L 0.16 0.64 Y Staphylococcus phage Twort YRN K+Q  -0.48 0.98 A A -0.61 0.91  
C Paramecium bursaria Chlorella virus C MYKD Human adenovirus type 10 CNM KD -0.01 0.03 R R 0.02 0.87 C C -0.99 0.11  
N Aeromonas phage NMY D -0.06 0.14 N N 0.50 0.52 R Human coronavirus NL63 RAL     MI A VLG Phage phiJL001 RAL   IAA  LGL     LLTV Sphaeropsis sapinea RNA virus  R LMIAA  LG Pennisetum mosaic virus R LMIAA V Recombinant M-MuLV/RaLV retrovirus RAL+   S LGLP I Peace Lily virus R LMI AS

-1.36 0.31  
M Human poliovirus 2 M K+ HHPA -0.06 0.95 G G 0.98 0.03 A Verticillium chrysogenum virus   ALMIAAS -1.34 0.04  
Y Y -0.05 0.97 K Hepatitis delta  KDQDG+ A P  R RT and KD DG+ A P 1.58 0.96 L Vibrio phage LM AASVLG St. Louis encephalitis virus  L+IAA VL   A+L  Alcelaphine herpesvirus 1 LMIAA  LG Grapevine chrome mosaic virus LMIAA Actinoplanes phage  L IA  V GLPAI


-1.39 0.55  
K K 0.25 0.86 D D 2.05 0.04 M Saffold virus MIAASVL Clostridium phage MIA    GLP IL mycobacterium phage  MI   V GLPAIL Hepatitis C  MIAA V


-1.25 0.14  
D Equid herpesvirus 9  DSH+ ART + 0.45 0.04 Q Q 2.34 0.40 I I -1.34 0.30  
S Cytomegalovirus SHH  RT 0.62 0.03 D Streptococcus phage +GD  PEY 2.37 0.03 A Choristoneura fumiferana DEF MNPV and Anticarsia gemmatalis nucleopolyhedrovirus AASV G   +L LL Synechococcus phage AASV GLPA Mycobacterium phage AA V+   GLPA+L

-1.60 0.11  
H H 1.05 0.03 G G 2.35 0.10 A A -1.34 0.04  
H Plum bark necrosis stem pitting-associated virus  Grouper iridovirus HPARTA  Rice gall dwarf virus HPAR 1.22 0.03 D D 2.39 0.02 S Feline immunodeficiency virus SVLG    ILLL   LP    CIR Klebsiella phage SVLG+ AI -1.14 0.04  
P P 1.13 0.38 Q Mycobacterium phage QAP YRG  EL Lymphocystis disease virus Q  E  GRT   K  I +GK 2.15 0.03 V V -0.82 0.43  
A Rotavirus A ARTAHY 0.97 0.95 A A 2.01 0.07 L Human rhinovirus LGLP I -0.54 0.92  
R Enterobacteria phage RTAHY 0.80 0.56 P Influenza b PEYRGR  LL Staphylococcus phage Twort and Bat coronavirus PEYR 1.78 0.11 G G -0.72 0.03  
T Moussa virus TAHYGS 0.72 0.05 E E 1.67 0.04 L L -1.11 0.18  
A Rice gall dwarf virus AHYG 0.80 0.48 Y Raniid herpesvirus 2 YR RTELLK 1.46 0.95 P Hepatitis b P IL L  V PCI Human rhinovirus PAIL LL  V    R    P V KY
-1.67 0.03  
H Porcine reproductive and respiratory syndrome virus HYG LP Avian paramyxovirus  HY SLP  S+ G TQD 0.61 0.79 R Streptococcus phage RGR  +LL +A+ 1.20 0.15 A West Nile virus Koutango virus AILLLL  Ostreid herpesvirus 1 AIL LLT Sandfly fever sicilian virus AILLL  V
-1.98 0.07  
Y Sulfolobus virus Gordonia terrae phage YGSLPQ
0.61 0.97 G Rhizobium phage G TELLK AI Staphylococcus phage Twort G TEL 0.72 0.07 I Dengue virus 2 IL LLT V P  Bovine viral diarrhea virus  ILLL T L Canarypox virus Fowlpox virus ILLLL  LPC Pennisetum mosaic virus ILL L VL  I Acute bee paralysis virus ILLLL

-2.09 0.39  
G G 0.60 0.73 R Emiliania huxleyi virus RTEL K 0.29 0.06 L L -2.29 0.89  
S S 0.73 0.04 T  ELLKDA+G 0.06 0.24 L Aeromonas phage LLLTVLP -2.24 0.93  
L L 0.92 0.84 E Mycobacterium phage  ELLKDA+G Lactobacillus phage ELLKD I Human astrovirus ELLK+ I 0.10 0.04 L L -2.58 0.87  
P P 0.93 0.07 L  Enterobacteria phage LLKD  0.05 0.97 L L -2.62 0.84  
Q Q 1.10 0.15 L Marseille virusL  AIG GK T  -0.19 0.96 T HIV-1 T+LPC     IRM QE G A Y Spodoptera exiguae ascovirus and Heliotis virescens ascovirus 3e TV  C RMGQ
-2.47 0.06  
K K 1.15 0.93 K K -0.16 0.80 V hepatitis b V PCI  -2.29 0.67  
S Cytomegalovirus SHG 1.15 0.13 D Cherry rasp leaf virus DAIGE K      RNV -0.06 0.03 L Hepatitis c LPC     EP VA HIV-1 LPC IR    MG E G A Y
-1.87 0.67  
H Musca domestica salivary gland hypertrophy virus HGRT DE  +VH 1.43 0.73 A Canine papillomavirus A GEG V L 0.06 0.18 P P -1.59 0.51  
G Cherry necrotic rusty mottle virus GRTQD 1.61 0.26 I I 0.50 0.06 C C -1.06 0.05  
R R 1.75 0.96 G Listeris phage GE  VTL  R V FSD  GF Human coxsackie virus and Human poliovirus 2 and 3 Human enterovirus GEG V  Hepatitis delta G GK  LR 0.64 0.03 I I -0.70 0.97  
T Ornithogalum mosaic virus TQDENP 1.78 0.14 E E 0.62 0.02 R hepatitis b R+G +P        QLAG -0.21 0.52  
Q White clover mosaic virus Q +NPVV+ F Alfalfa mosaic virus QDENPV Pepino mosaic virus Q ENPVV+ F Saffold virus Q  NPV 1.69 0.03 G Human rhinovirus GK + L  R+ NVRFS 0.14 0.23 M M 0.23 0.85  
D Feline herpesvirus 1 +DENPVVSaffold virus + ENPV 1.56 0.03 K Lettuce infectious yellows virus KVTLRI 0.05 0.11 G G 0.56 0.05  
E Foot and mouth virus +NPVVH 1.29 0.03 V V -0.12 0.34 Q Prochlorococcus phage QEPGVA Y   QL G  Cytomegalovirus Q P     RR   A VLLI   LC L     FP

 
Emiliania huxleyi virus  Q  GV KYRR
0.69 0.03  
N Adoxophyes honmai NPV +FK IVTP 1.02 0.02 T Fowlpox virus TLRI N+R -0.31 0.02 E Oliveros virus  EP VA  R        LIL+ LC 0.96 0.02  
P Deftia phage PV V  FKNIV  0.46 0.02 L Cytomegalovirus LR RNVRF Streptococcus pyogenes phage LRIRN   SD -0.48 0.96 P P 1.09 0.02  
V   -0.03 0.44 R Human rhinovirus 3 R+ NVRFS Burkholderia Phage RIRN    VRF D -0.85 0.12 G G 1.17 0.02  
V Saffold virus V   KN VTP T -0.35 0.69 I Acanthocystis turfacea Chlorella virus I NVRFS +G -1.00 0.90 V Mycobacterium phage V KYRRA 1.09 0.73  
H Bean pod mottle virus HFFKN Turnip ringspot virus HFF NI TP

-0.68 0.25 R Turkey adenovirus A RNV FS+E  GGF  Human poliovirus 1 R V FSD  -1.12 0.05 A Vibrio phage AKYRRA 0.91 0.13  
F Clostridium phage Lactococcus phage FFKNIV Ovine herpesvirus 2 FFKNIV Shrimp white spot syndrome virus FFKNI  Synechococcus phageFFKN+V P Marseillevirus FF N  T RTPP
 
-1.17 0.82 N Enterococcus phage NVR   SDEG FT F -0.99 0.03 K Gallid herpesvirus 1 KYRRA    QLA 0.49 0.76  
F Acinetobacter phage F +IVTP T -1.31 0.44 V Enterobacteria phage VRF D GG+ CF+ D S+ -0.39 0.96 Y Y 0.40 0.98  
K Theiler's encephalomyelitis virus KNIV P T KNI+T RT
Prochlorococcus phage
-1.14 0.82 R R -0.04 0.61 R Meleagrid herpesvirus 1 RRA L G VLL   ALC Gallid herpesvirus 2 RRA L G L  LL ALC -0.05 0.60  
N Acinetobacter phage NIVTP T Ateline herpesvirus 3 NIV PRT -0.90 0.57 F F 0.44 0.94 R R -0.12 0.35  
I Porcine epidemic diarrhea virus IV P TPP S  Pseudomonas phage IVTPRT
-0.44 0.82 S Synechococcus phage SDEG F 0.64 0.03 A A -0.14 0.12  
V TPRTP Glossina pallidipes salivary gland hypertrophy virus  Human enterovirus 70  VTP TP P Human echovirus 6 or 30 Human enterovirus 101 Drosophila affinis sigma virus VTP TPPP

0.33 0.93 D D 0.39 0.04 Q St. Louis encephalitis virus Q AGVLLI  LL Hepatitis b QLAG  -0.38 0.02  
T Norovirus TPR PPP  G JC Polyomavirus TP TPPP Merkel cell polyomavirus TP TPPP Phthorimaea operculella granulovirus TP TPPPS+ Rock bream iridovirus Orange-spotted grouper iridovirus  TPPP  GK

0.97 0.30 E Meleagrid herpesvirus 1 EG  TCFFR+ Bat coronavirus EGGFT 0.55 0.03 L Bovine viral diarrhea virus LAG LL    ILL    +VAT W -0.68 0.56  
P JC polyomavirus PRTPPP  Porcine reproductive and respiratory syndrome virus  PRTP PS Physalis mottle virus PRT PP Ovine herpesvirus 2 PR PP PS

1.37 0.82 G Hepatitis delta GGFT 0.35 0.03 A Bovine viral diarrhea virus  AG+LL    ILL Bovine viral diarrhea virus 1-Osloss  AG+LL    ILL    L+AT W Human calcivirus Sapovirus AGV LILL
-1.20 0.07  
R Theiler's encephalomyelitis virus RTPPP  Torque teno mini virus  Orange-spotted  grouper iridovirus R PPPSQ
1.74 0.86 G Hepatitis c GFT FFR  Pipistrellus bat and BAT coronavirus GFTCF
0.22 0.02 G Choristoneura fumiferana DEF MNPV and Anticarsia gemmatalis nucleopolyhedrovirus and Hyphantria cunea nucleopolyhedrovirus G+ LILL L  LV   W P Rachiplusia nu MNPV G+ LILL L  LV   W -1.73 0.03  
T TP TPPP  Nakiwogo virusTPPPS
2.37 0.07 F Infectious bronchitis virus FTC+F -0.27 0.62 V Crimean-Congo hemorrhagic fever virus VLLI LALC L Impatiens necrotic spot virus+LLIL    LA LC  VAT Enterobacteria phage V LILL  Kinjin virus V+LIL  L ALV -2.11 0.28  
P Ovine herpesvirus 2 PPPSQG 2.72 0.03 T T -0.54 0.05 L Salmonella phage LLIL+AL ALV  I -2.62 0.57  
P Feline herpesvirus 1 PP QGK 2.83 0.03 C Human poliovirus 1 RD H Y+EE AME -0.66 0.16 L Oliveros virus LIL+ LC  Xanthomonas phage +LILLAL
-2.66 0.37  
P Hepatitis B P QG G  LS 2.90 0.39 F F -0.81 0.96 I I -3.01 0.70  
S S 2.83 0.13 F F -0.84 0.62 L Norovirus LLALCAL -3.17 0.88  
Q Eimeria brunetti RNA virus QGKGR HIV-1 QGK RG S
2.50 0.49 R Human coxsackie virus and human poliovirus 1, 2 and 3  and Human enterovirus RD H Y+EE AME
-0.65 0.25 L L -3.18 0.62  
G G 2.30 0.83 D Influenza a DHS Y EEA M+ Feline coronavirus D SYQE  -0.46 0.08 A A -3.17 0.30  
K Influenza A KGRGL Enterobacteria phage KGRG S S FS
1.65 0.96 H Human coxsackievirus  H   EE AME -0.06 0.13 L L -2.84 0.66  
G Infectious hematopoietic necrosis virus GRGL L R S G 1.35 0.53 S S 0.55 0.02 C Meleagrid herpesvirus 1 CAL+AT -2.48 0.03  
R Pyrococcus abyssi virus RGLSL Hepatitis B RGL    FS  Durham virus G+SLSRF
0.65 0.71 Y Aeromonas phage Y  E AMELK VE Enterobacteria phage YQEE 0.92 0.88 A Cassava brown streak virus ALVATI Equine herpesvirus 9 ALV TI   WF V
-2.01 0.13  
G Paramecium bursaria Chlorella virus GLSLSRF 0.38 0.08 Q Q 0.97 0.11 L Southern cowpea mosaic virus LVA  W F VCA -1.84 0.50  
L L 0.15 0.77 E BK polyomavirus  EEA  EL 0.63 0.10 V Pseudaletia unipuncta granulovirus Xestia c-nigrum granulovirus VA   FPVC + +TT -1.80 0.38  
S S -0.27 0.03 E E 0.67 0.04 A A -1.67 0.07  
L L -0.38 0.93 A Synechococcus phage AAMELK  +DP  Swine fever AAME 0.19 0.16 T T -1.54 0.02  
S S -0.66 0.07 A GB virus D | A + LKVED 0.28 0.08 I Bunyamwera virus Tensaw virus  IWFP -1.46 0.49  
R R -0.60 0.63 M M -0.02 0.80 W W -1.09 0.18  
F F -0.20 0.93 E E 0.05 0.04 F F -1.06 0.18  
S S 0.00 0.03 L L 0.08 0.90 P Newcastle disease virus PVC HR T -0.97 0.07  
W W 0.48 0.97 K BK polyomavirus KVEDP Feline coronavirus  KVE  D FY 0.18 0.13 V V -0.92 0.94  
G HIV-1 GAEGQR G Avian leukosis virus G +GQRPG 0.73 0.10 V V 0.02 0.11 C C -0.49 0.05  
A Orange-spotted grouper iridovirus Turbot reddish body iridovirus  HIV-1 AEGQR 1.00 0.93 E E 0.13 0.02 A JC Polyomavirus A+RE T +SFGYS Y   I  -0.21 0.38  
E HSV-2 EG+RPG 1.36 0.03 D Influenza a DPFYW S   L   AV Influenza C DPFYW S -0.24 0.03 H H 0.10 0.35  
G G 1.47 0.72 P Feline coronavirus PF W+SP 0.06 0.03 R Sugarcane yellow leaf virus RE TI S  F GYSL Cycas necrotic stunt virus RETTI+  SF  S  Synechococcus phage RETTIV -0.09 0.92  
Q Q 1.58 0.04 F F 0.24 0.31 E Anatid herpesvirus  ETTIV F Ostreococcus virus  ET  VS    LYAGWI -0.15 0.02  
R Bovine herpesvirus 5 RPG GY GRAS Lactococcus phage RPGFGYG
1.54 0.37 Y Y 0.48 0.77 T T -0.13 0.16  
P Citrus yellow mosaic virus PG+ YGGR S+ Equine papillomavirus PGFG 1.41 0.02 W W 0.37 0.67 T T -0.26 0.02  
G G 1.32 0.03 V Cherry rasp leaf virus VSP  L L +A 0.04 0.75 I Cydia pomonella granulovirus IVS    L   W+  VLCL GG -0.12 0.08  
F F 1.31 0.44 S Canine papillomavirus SP V VL -0.44 0.06 V  Epstein-Barr VS G  LYA WIG -0.33 0.61  
G G 1.21 0.03 P P -0.66 0.03 S S -0.42 0.04  
Y Y 1.06 0.84 G Acinetobacter phage G L +LAVL V+L -1.02 0.19 F F -0.78 0.96  
G Bacillus phage GGRA SDY
1.09 0.34 V Infectious bronchitis virus VL LL V  V LLQI  Influenza a VLLAV
-1.11 0.69 G Human coronavirus GYSLY  W     CL+G Oliveros virus GYSLY    G VL L
-0.91 0.03  
G Bacillus phage GRASDY 1.11 0.47 L L -1.29 0.91 Y Y -0.72 0.96  
R Broad bean wilt virus Patchouli mild mosaic virus RASDYK 1.19 0.91 V Measles VLLAVL V+ L Xestia c-nigrum granulovirus VLLA LP+  LQI Equid herpesvirus 1 and 9 VL VLLLQ T G   L -1.66 0.56 S Broad bean wilt virus SL+ GWI  V LCLV -0.43 0.03  
A Equine papillomavirus ASDYK 1.18 0.21 L Influenza a LL I VGL+F+C -2.01 0.95 L L -0.64 0.96  
S S 1.31 0.02 L Enterovirus 103 LAV PV  LQ -2.24 0.94 Y Varicella YA W G   AV  LCLV Vibrio Phage  Y GWIGA
-0.53 0.97  
D Influenza A DYKS 1.15 0.04 A A -2.37 0.25 A Klebsiella phage AGWIG -0.58 0.10  
Y Y 1.06 0.97 V VLPVL Gill-associated virus VLPVL  Human adenovirus 41 V  VL L I VGLI  -2.33 0.35 G G -0.55 0.02  
K K 0.97 0.27 L L -2.39 0.49 W W -0.84 0.17  
S S 0.95 0.04 P Mycobacterium phage  PVLL  -2.41 0.04 I I -0.99 0.24  
A A 0.62 0.25 V Feline coronavirus VL  LL+I -2.04 0.80 G G -1.17 0.02  
H Tanapox and Yaba viruses HKGFK 0.48 0.22 L Influenza a LLL I  GL+F+C Infectious bronchitis virus LLL ITV  GL Fowl plaque virus LL I VGL+F C -2.13 0.84 A Sphaeropsis sapinea RNA virus  AVL LVG -1.56 0.85  
K K 0.58 0.86 L Influenza a LL I  GLIF+C Equine coronavirus LL+IT+ -1.93 0.47 V V -1.83 0.80  
G Cowpox rabbitpox Vaccinia and Variola Ectromelia virus  GFKGVD 0.40 0.12 L Enterobacteria phage LQITVG Synechococcus phage L QITV
-1.88 0.92 L Venezuelan equine encephalitis virus LCLV    +LCCA -1.64 0.96  
F Sunflower chlorotic mottle virus FK  VDAQGT Hepatitis C  F GVDAQ   0.54 0.92 Q Q -1.80 0.06 C Guman herpesvirus 5 CLV  CV LC  C G  -1.46 0.04  
K K 0.57 0.12 I I -1.97 0.51 L L -1.59 0.56  
G Hepatitis B GV+AQG 0.71 0.04 T T -2.01 0.04 V Human coronavirus NL63 VGGCV Clostridium phage VG   ILC   DA AFG -1.76 0.22  
V Hepatitis B V+AQG L K+  0.75 0.90 V V -2.09 0.29 G G -2.03 0.03  
D D 0.79 0.05 G Hepatitis c GLIF C     RG L Human astrovirus G IFLC -2.17 0.13 G G -2.11 0.03  
A Hepatitis B AQGTLS + 0.77 0.12 L L -2.35 0.90 C Bat coronavirus CV  ILCC G -2.08 0.02  
Q Synechococcus phage HIV-1 QGTLS 0.72 0.03 I I -2.46 0.63 V V -1.82 0.50  
G Bacillus phage GTLSK 0.59 0.17 F F -2.57 0.29 I I -1.68 0.24  
T Nakiwogo virus TLSKIF HIV-1 TLSKI  KL  Lactococcus phage TLSKI 0.37 0.02 L L -2.57 0.87 L L -1.57 0.98  
L Hepatitis C L  IF LG -0.25 0.86 C Canine papillomavirus CL YRL G  R -2.60 0.03 C Human herpesvirus 8 CCAGD Peanut mottle virus CC  D   F  NRFY -1.31 0.03  
S HIV-1 SKIF  GG -0.33 0.08 L Enterobacteria phage L YRLR -2.51 0.97 C HIV-1 CA DAQA+ E -1.12 0.04  
K K -0.80 0.82 Q Cytomegalovirus Q RLR Dengue virus +YRLRG  R  -2.11 0.04 A A -0.73 0.05  
  Aphid lethal paralysis virus IF LGGR HIV-1 IF LGG  -0.81 0.81 Y Y -1.59 0.97 G Human herpesvirus 8 GD  AF     Y TA    SPTHA Synechococcus phage G+AQAF E and GDAQ   + RFY  Klebsiella phage GDA+AF

-0.23 0.03  
  Adeno-associated virus FKL GRDS -0.79 0.71 R R -1.02 0.18 D D 0.11 0.02  
  K -0.40 0.28 L L -1.03 0.96 A A 0.49 0.04  
  Norwalk virus LGGRD R SG P -0.18 0.97 R Pipistrellus bat and Bat coronavirus RGK RAE  Streptomyces Phage RG LRAE+E L -0.58 0.05 Q Measles Q  GE R  Y  AGSS    A SAH Synechococcus phage Q FGEN +Y
0.80 0.03  
  Brochothrix phage GGRDS 0.02 0.72 G Tamana bat virus GKLRAEI+N Emiliania huxleyi virus GKLRAE
-0.63 0.04 A A 1.00 0.06  
  Bovine herpesvirus 1 GR+ R  S MAR Plum bark necrosis stem pitting-associated virus G RDSR
0.44 0.09 K Listonella phage KLR EI++L Helicoverpa armigera granulovirus  KL AEIEN  -0.30 0.14 F Human rhinovirus FGEN FY 0.90 0.07  
  Polyomavirus HPyV7 RD RSGSPM 1.00 0.47 L Alcelaphine herpesvirus 1 LRA+I N -0.43 0.63 G G 0.32 0.02  
  Lactobacillus phage+SRSG P Staphylococcus phage DS SGS 1.30 0.15 R Cyprinid herpesvirus 3 RAEIE L Acanthamoeba polyphaga mimivirus RAEI -0.06 0.14 E Rhodothermus phage ENRFYY Bovine herpesvirus 4 E+RFYY
0.06 0.02  
  S 1.78 0.03 A A -0.05 0.79 N N -0.19 0.03  
  R 1.82 0.34 E E -0.33 0.02 R Equid herpesvirus 4 R  YTA  SS  HA  AH -0.10 0.06  
  S 1.64 0.04 I  Synechococcus phage IEN -0.43 0.73 F F 0.14 0.90  
  G 1.49 0.03 E E -0.26 0.02 Y Y 0.20 0.95  
  S 1.23 0.02 N shrimp white spot syndrome virus NLHRTF -0.24 0.03 Y Prochlorococcus phage  YTAGS 0.26 0.96  
  P 1.11 0.35 L Cytomegalovirus  LHR F Q   ELRN + -0.36 0.85 T Synechococcus phage TAGS  PTH  Prochlorococcus phage T GSS PTH 0.43 0.26  
  M 1.07 0.81 H H -0.43 0.27 A Cytomegalovirus A SSS TH 0.69 0.91  
  A 0.96 0.70 R Synechococcus phage RTFG  -0.26 0.44 G G 1.15 0.16  
  R 0.71 0.95 T T -0.59 0.08 S Epstein-Barr SS P HA 1.51 0.22  
  R 0.42 0.48 F Human herpesvirus 8 FGQFLEE  Synechococcus phage FG FLEE -0.89 0.72 S S 1.78 0.05  
        G G -0.60 0.03 S S 1.71 0.05  
        Q Q -0.51 0.04 P P 1.77 0.27  
        F Dengue virus FLEE LR -0.68 0.93 T T 1.71 0.10  
        L Alcelaphine herpesvirus 1 LEEL -0.60 0.85 H H 1.47 0.13  
        E E -0.28 0.23 A A 1.14 0.66  
        E E -0.27 0.20 K K 0.71 0.95  
        L L -0.42 0.87 S S 0.61 0.52  
        R R -0.21 0.05 A A 0.40 0.46  
        N N 0.09 0.06 H H 0.23 0.42  
        P P 0.06 0.06 V V 0.21 0.95  
        F F -0.03 0.84          
January 27, 2011 "