Search PATHWAY

hsa05010 Alzheimer's disease - Homo sapiens (human) (19)

hsa:102 ADAM10; ADAM metallopeptidase domain 10 (EC:3.4.24.81) hsa:348 APOE; apolipoprotein E hsa:351 APP; amyloid beta (A4) precursor protein hsa:23621 BACE1; beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) hsa:1020 CDK5; cyclin-dependent kinase 5 (EC:2.7.11.22) hsa:8851 CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35) hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3416 IDE; insulin-degrading enzyme (EC:3.4.24.56) hsa:3553 IL1B; interleukin 1, beta hsa:4137 MAPT; microtubule-associated protein tau hsa:23385 NCSTN; nicastrin hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) hsa:5663 PSEN1; presenilin 1 (EC:3.4.23.-) hsa:5664 PSEN2; presenilin 2 (Alzheimer disease 4) hsa:55851 PSENEN; presenilin enhancer 2 homolog (C. elegans) hsa:6622 SNCA; synuclein, alpha (non A4 component of amyloid precursor) hsa:7124 TNF; tumor necrosis factor

hsa05323 Rheumatoid arthritis - Homo sapiens (human) (14)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:6348 CCL3; chemokine (C-C motif) ligand 3 hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4314 MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human) (13)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:6348 CCL3; chemokine (C-C motif) ligand 3 hsa:729230 CCR2; chemokine (C-C motif) receptor 2 hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3586 IL10; interleukin 10 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05152 Tuberculosis - Homo sapiens (human) (13)

hsa:929 CD14; CD14 molecule hsa:1378 CR1; complement component (3b/4b) receptor 1 (Knops blood group) hsa:1509 CTSD; cathepsin D (EC:3.4.23.5) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa05144 Malaria - Homo sapiens (human) (12)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:948 CD36; CD36 molecule (thrombospondin receptor) hsa:1378 CR1; complement component (3b/4b) receptor 1 (Knops blood group) hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3586 IL10; interleukin 10 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa05164 Influenza A - Homo sapiens (human) (12)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:7124 TNF; tumor necrosis factor

hsa05200 Pathways in cancer - Homo sapiens (human) (11)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18) hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) hsa:6256 RXRA; retinoid X receptor, alpha hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human) (11)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:6348 CCL3; chemokine (C-C motif) ligand 3 hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3586 IL10; interleukin 10 hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa05168 Herpes simplex infection - Homo sapiens (human) (11)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:5819 PVRL2; poliovirus receptor-related 2 (herpesvirus entry mediator B) hsa:6891 TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa05140 Leishmaniasis - Homo sapiens (human) (10)

hsa:1378 CR1; complement component (3b/4b) receptor 1 (Knops blood group) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa04640 Hematopoietic cell lineage - Homo sapiens (human) (9)

hsa:929 CD14; CD14 molecule hsa:945 CD33; CD33 molecule hsa:948 CD36; CD36 molecule (thrombospondin receptor) hsa:1378 CR1; complement component (3b/4b) receptor 1 (Knops blood group) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:7124 TNF; tumor necrosis factor

hsa05162 Measles - Homo sapiens (human) (9)

hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:7097 TLR2; toll-like receptor 2 hsa:7157 TP53; tumor protein p53 hsa:7161 TP73; tumor protein p73

hsa04010 MAPK signaling pathway - Homo sapiens (human) (9)

hsa:929 CD14; CD14 molecule hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:9479 MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1 hsa:4137 MAPT; microtubule-associated protein tau hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa05146 Amoebiasis - Homo sapiens (human) (9)

hsa:929 CD14; CD14 molecule hsa:3586 IL10; interleukin 10 hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa05134 Legionellosis - Homo sapiens (human) (8)

hsa:929 CD14; CD14 molecule hsa:1378 CR1; complement component (3b/4b) receptor 1 (Knops blood group) hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa05132 Salmonella infection - Homo sapiens (human) (8)

hsa:6348 CCL3; chemokine (C-C motif) ligand 3 hsa:929 CD14; CD14 molecule hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)

hsa05133 Pertussis - Homo sapiens (human) (8)

hsa:929 CD14; CD14 molecule hsa:3586 IL10; interleukin 10 hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:7124 TNF; tumor necrosis factor

hsa05166 HTLV-I infection - Homo sapiens (human) (8)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3932 LCK; lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human) (8)

hsa:904 CCNT1; cyclin T1 hsa:929 CD14; CD14 molecule hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:4314 MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17) hsa:5327 PLAT; plasminogen activator, tissue (EC:3.4.21.68) hsa:6256 RXRA; retinoid X receptor, alpha hsa:7157 TP53; tumor protein p53

hsa05143 African trypanosomiasis - Homo sapiens (human) (8)

hsa:335 APOA1; apolipoprotein A-I hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3586 IL10; interleukin 10 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:7124 TNF; tumor necrosis factor

hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human) (7)

hsa:6348 CCL3; chemokine (C-C motif) ligand 3 hsa:929 CD14; CD14 molecule hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa04145 Phagosome - Homo sapiens (human) (7)

hsa:929 CD14; CD14 molecule hsa:948 CD36; CD36 molecule (thrombospondin receptor) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) hsa:4973 OLR1; oxidized low density lipoprotein (lectin-like) receptor 1 hsa:6891 TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) hsa:7097 TLR2; toll-like receptor 2

hsa05169 Epstein-Barr virus infection - Homo sapiens (human) (7)

hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3586 IL10; interleukin 10 hsa:7157 TP53; tumor protein p53 hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human) (6)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:3576 IL8; interleukin 8 hsa:7124 TNF; tumor necrosis factor

hsa05145 Toxoplasmosis - Homo sapiens (human) (6)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7097 TLR2; toll-like receptor 2 hsa:7124 TNF; tumor necrosis factor

hsa01100 Metabolic pathways - Homo sapiens (human) (6)

hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) hsa:4539 ND4L; NADH dehydrogenase, subunit 4L (complex I) hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:5444 PON1; paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa05332 Graft-versus-host disease - Homo sapiens (human) (6)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:7124 TNF; tumor necrosis factor

hsa05160 Hepatitis C - Homo sapiens (human) (6)

hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3576 IL8; interleukin 8 hsa:6256 RXRA; retinoid X receptor, alpha hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa04722 Neurotrophin signaling pathway - Homo sapiens (human) (6)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:5663 PSEN1; presenilin 1 (EC:3.4.23.-) hsa:5664 PSEN2; presenilin 2 (Alzheimer disease 4) hsa:7157 TP53; tumor protein p53 hsa:7161 TP73; tumor protein p73 hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

hsa04062 Chemokine signaling pathway - Homo sapiens (human) (5)

hsa:6347 CCL2; chemokine (C-C motif) ligand 2 hsa:6348 CCL3; chemokine (C-C motif) ligand 3 hsa:729230 CCR2; chemokine (C-C motif) receptor 2 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3576 IL8; interleukin 8

hsa04940 Type I diabetes mellitus - Homo sapiens (human) (5)

hsa04380 Osteoclast differentiation - Homo sapiens (human) (5)

hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3932 LCK; lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor

hsa05020 Prion diseases - Homo sapiens (human) (5)

hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:5621 PRNP; prion protein

hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human) (5)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3932 LCK; lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) hsa:100507436 MICA; MHC class I polypeptide-related sequence A hsa:7124 TNF; tumor necrosis factor

hsa04210 Apoptosis - Homo sapiens (human) (5)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3552 IL1A; interleukin 1, alpha hsa:3553 IL1B; interleukin 1, beta hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa05330 Allograft rejection - Homo sapiens (human) (4)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:7124 TNF; tumor necrosis factor

hsa04672 Intestinal immune network for IgA production - Homo sapiens (human) (4)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:7040 TGFB1; transforming growth factor, beta 1

hsa05222 Small cell lung cancer - Homo sapiens (human) (4)

hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) hsa:6256 RXRA; retinoid X receptor, alpha hsa:7157 TP53; tumor protein p53

hsa04610 Complement and coagulation cascades - Homo sapiens (human) (4)

hsa:2 A2M; alpha-2-macroglobulin hsa:3075 CFH; complement factor H (EC:4.2.1.2) hsa:1378 CR1; complement component (3b/4b) receptor 1 (Knops blood group) hsa:5327 PLAT; plasminogen activator, tissue (EC:3.4.21.68)

hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human) (4)

hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:4000 LMNA; lamin A/C hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor

hsa04660 T cell receptor signaling pathway - Homo sapiens (human) (4)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:3586 IL10; interleukin 10 hsa:3932 LCK; lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) hsa:7124 TNF; tumor necrosis factor

hsa03320 PPAR signaling pathway - Homo sapiens (human) (4)

hsa:335 APOA1; apolipoprotein A-I hsa:948 CD36; CD36 molecule (thrombospondin receptor) hsa:4973 OLR1; oxidized low density lipoprotein (lectin-like) receptor 1 hsa:6256 RXRA; retinoid X receptor, alpha

hsa04110 Cell cycle - Homo sapiens (human) (4)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7157 TP53; tumor protein p53 hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human) (4)

hsa:3606 IL18; interleukin 18 (interferon-gamma-inducing factor) hsa:3553 IL1B; interleukin 1, beta hsa:3569 IL6; interleukin 6 (interferon, beta 2) hsa:81030 ZBP1; Z-DNA binding protein 1

hsa04330 Notch signaling pathway - Homo sapiens (human) (4)

hsa:23385 NCSTN; nicastrin hsa:5663 PSEN1; presenilin 1 (EC:3.4.23.-) hsa:5664 PSEN2; presenilin 2 (Alzheimer disease 4) hsa:55851 PSENEN; presenilin enhancer 2 homolog (C. elegans)

hsa05150 Staphylococcus aureus infection - Homo sapiens (human) (4)

hsa:3075 CFH; complement factor H (EC:4.2.1.2) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:3586 IL10; interleukin 10

hsa04612 Antigen processing and presentation - Homo sapiens (human) (4)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) hsa:6891 TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) hsa:7124 TNF; tumor necrosis factor

hsa05219 Bladder cancer - Homo sapiens (human) (3)

hsa:3576 IL8; interleukin 8 hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human) (3)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1 hsa:5819 PVRL2; poliovirus receptor-related 2 (herpesvirus entry mediator B)

hsa05210 Colorectal cancer - Homo sapiens (human) (3)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7157 TP53; tumor protein p53

hsa05310 Asthma - Homo sapiens (human) (3)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:7124 TNF; tumor necrosis factor

hsa04310 Wnt signaling pathway - Homo sapiens (human) (3)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:5663 PSEN1; presenilin 1 (EC:3.4.23.-) hsa:7157 TP53; tumor protein p53

hsa05322 Systemic lupus erythematosus - Homo sapiens (human) (3)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10 hsa:7124 TNF; tumor necrosis factor

hsa05215 Prostate cancer - Homo sapiens (human) (3)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18) hsa:7157 TP53; tumor protein p53

hsa05414 Dilated cardiomyopathy - Homo sapiens (human) (3)

hsa:4000 LMNA; lamin A/C hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor

hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human) (3)

hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) hsa:7124 TNF; tumor necrosis factor hsa:7157 TP53; tumor protein p53

hsa05320 Autoimmune thyroid disease - Homo sapiens (human) (3)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3586 IL10; interleukin 10

hsa04360 Axon guidance - Homo sapiens (human) (3)

hsa:1020 CDK5; cyclin-dependent kinase 5 (EC:2.7.11.22) hsa:1808 DPYSL2; dihydropyrimidinase-like 2 hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa04920 Adipocytokine signaling pathway - Homo sapiens (human) (3)

hsa:948 CD36; CD36 molecule (thrombospondin receptor) hsa:6256 RXRA; retinoid X receptor, alpha hsa:7124 TNF; tumor necrosis factor

hsa05212 Pancreatic cancer - Homo sapiens (human) (3)

hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7157 TP53; tumor protein p53 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04115 p53 signaling pathway - Homo sapiens (human) (3)

hsa:355 FAS; Fas (TNF receptor superfamily, member 6) hsa:7157 TP53; tumor protein p53 hsa:7161 TP73; tumor protein p73

hsa05340 Primary immunodeficiency - Homo sapiens (human) (2)

hsa:3932 LCK; lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) hsa:6891 TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

hsa04726 Serotonergic synapse - Homo sapiens (human) (2)

hsa:351 APP; amyloid beta (A4) precursor protein hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa04970 Salivary secretion - Homo sapiens (human) (2)

hsa:1471 CST3; cystatin C hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)

hsa05016 Huntington's disease - Homo sapiens (human) (2)

hsa:6648 SOD2; superoxide dismutase 2, mitochondrial (EC:1.15.1.1) hsa:7157 TP53; tumor protein p53

hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human) (2)

hsa:5610 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2) hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

hsa04370 VEGF signaling pathway - Homo sapiens (human) (2)

hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human) (2)

hsa:929 CD14; CD14 molecule hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

hsa04975 Fat digestion and absorption - Homo sapiens (human) (2)

hsa:335 APOA1; apolipoprotein A-I hsa:948 CD36; CD36 molecule (thrombospondin receptor)

hsa05030 Cocaine addiction - Homo sapiens (human) (2)

hsa:1020 CDK5; cyclin-dependent kinase 5 (EC:2.7.11.22) hsa:8851 CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35)

hsa05223 Non-small cell lung cancer - Homo sapiens (human) (2)

hsa:6256 RXRA; retinoid X receptor, alpha hsa:7157 TP53; tumor protein p53

hsa04510 Focal adhesion - Homo sapiens (human) (2)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) (2)

hsa:102 ADAM10; ADAM metallopeptidase domain 10 (EC:3.4.24.81) hsa:3576 IL8; interleukin 8

hsa04146 Peroxisome - Homo sapiens (human) (2)

hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39) hsa:6648 SOD2; superoxide dismutase 2, mitochondrial (EC:1.15.1.1)

hsa00330 Arginine and proline metabolism - Homo sapiens (human) (2)

hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)

hsa04350 TGF-beta signaling pathway - Homo sapiens (human) (2)

hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7124 TNF; tumor necrosis factor

hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human) (2)

hsa:3576 IL8; interleukin 8 hsa:7124 TNF; tumor necrosis factor

hsa05416 Viral myocarditis - Homo sapiens (human) (2)

hsa:3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1 hsa:3383 ICAM1; intercellular adhesion molecule 1

hsa04512 ECM-receptor interaction - Homo sapiens (human) (2)

hsa:948 CD36; CD36 molecule (thrombospondin receptor) hsa:3339 HSPG2; heparan sulfate proteoglycan 2

hsa05012 Parkinson's disease - Homo sapiens (human) (2)

hsa:4539 ND4L; NADH dehydrogenase, subunit 4L (complex I) hsa:6622 SNCA; synuclein, alpha (non A4 component of amyloid precursor)

hsa04630 Jak-STAT signaling pathway - Homo sapiens (human) (2)

hsa:3586 IL10; interleukin 10 hsa:3569 IL6; interleukin 6 (interferon, beta 2)

hsa05217 Basal cell carcinoma - Homo sapiens (human) (2)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:7157 TP53; tumor protein p53

hsa05211 Renal cell carcinoma - Homo sapiens (human) (2)

hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7422 VEGFA; vascular endothelial growth factor A

hsa05220 Chronic myeloid leukemia - Homo sapiens (human) (2)

hsa:7040 TGFB1; transforming growth factor, beta 1 hsa:7157 TP53; tumor protein p53

hsa05216 Thyroid cancer - Homo sapiens (human) (2)

hsa:6256 RXRA; retinoid X receptor, alpha hsa:7157 TP53; tumor protein p53

hsa05213 Endometrial cancer - Homo sapiens (human) (2)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) hsa:7157 TP53; tumor protein p53

hsa04020 Calcium signaling pathway - Homo sapiens (human) (2)

hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) hsa:4843 NOS2; nitric oxide synthase 2, inducible (EC:1.14.13.39)

hsa04144 Endocytosis - Homo sapiens (human) (2)

hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:7040 TGFB1; transforming growth factor, beta 1

hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human) (2)

hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5) hsa:2099 ESR1; estrogen receptor 1

hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human) (1)

hsa:929 CD14; CD14 molecule

hsa04150 mTOR signaling pathway - Homo sapiens (human) (1)

hsa:7422 VEGFA; vascular endothelial growth factor A

hsa04721 Synaptic vesicle cycle - Homo sapiens (human) (1)

hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)

hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human) (1)

hsa:2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)

hsa00590 Arachidonic acid metabolism - Homo sapiens (human) (1)

hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa04976 Bile secretion - Homo sapiens (human) (1)

hsa:6256 RXRA; retinoid X receptor, alpha

hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human) (1)

hsa:7329 UBE2I; ubiquitin-conjugating enzyme E2I (EC:6.3.2.19)

hsa05214 Glioma - Homo sapiens (human) (1)

hsa:7157 TP53; tumor protein p53

hsa04725 Cholinergic synapse - Homo sapiens (human) (1)

hsa:1103 CHAT; choline O-acetyltransferase (EC:2.3.1.6)

hsa04910 Insulin signaling pathway - Homo sapiens (human) (1)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa04662 B cell receptor signaling pathway - Homo sapiens (human) (1)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human) (1)

hsa:7124 TNF; tumor necrosis factor

hsa00480 Glutathione metabolism - Homo sapiens (human) (1)

hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)

hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human) (1)

hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)

hsa04114 Oocyte meiosis - Homo sapiens (human) (1)

hsa:7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

hsa04340 Hedgehog signaling pathway - Homo sapiens (human) (1)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human) (1)

hsa:4000 LMNA; lamin A/C

hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human) (1)

hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)

hsa03410 Base excision repair - Homo sapiens (human) (1)

hsa:142 PARP1; poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)

hsa04730 Long-term depression - Homo sapiens (human) (1)

hsa:4842 NOS1; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)

hsa04012 ErbB signaling pathway - Homo sapiens (human) (1)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human) (1)

hsa:5743 PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)

hsa02010 ABC transporters - Homo sapiens (human) (1)

hsa:6891 TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

hsa04142 Lysosome - Homo sapiens (human) (1)

hsa:1509 CTSD; cathepsin D (EC:3.4.23.5)

hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human) (1)

hsa:1785 DNM2; dynamin 2 (EC:3.6.5.5)

hsa00190 Oxidative phosphorylation - Homo sapiens (human) (1)

hsa:4539 ND4L; NADH dehydrogenase, subunit 4L (complex I)

hsa04728 Dopaminergic synapse - Homo sapiens (human) (1)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa04930 Type II diabetes mellitus - Homo sapiens (human) (1)

hsa:7124 TNF; tumor necrosis factor

hsa03013 RNA transport - Homo sapiens (human) (1)

hsa:7329 UBE2I; ubiquitin-conjugating enzyme E2I (EC:6.3.2.19)

hsa05131 Shigellosis - Homo sapiens (human) (1)

hsa:3576 IL8; interleukin 8

hsa00564 Glycerophospholipid metabolism - Homo sapiens (human) (1)

hsa:1103 CHAT; choline O-acetyltransferase (EC:2.3.1.6)

hsa05218 Melanoma - Homo sapiens (human) (1)

hsa:7157 TP53; tumor protein p53

hsa04977 Vitamin digestion and absorption - Homo sapiens (human) (1)

hsa:335 APOA1; apolipoprotein A-I

hsa04520 Adherens junction - Homo sapiens (human) (1)

hsa:5819 PVRL2; poliovirus receptor-related 2 (herpesvirus entry mediator B)

hsa04916 Melanogenesis - Homo sapiens (human) (1)

hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)

hsa03060 Protein export - Homo sapiens (human) (1)

hsa:3309 HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

hsa04670 Leukocyte transendothelial migration - Homo sapiens (human) (1)

hsa:3383 ICAM1; intercellular adhesion molecule 1

hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human) (1)

hsa:2950 GSTP1; glutathione S-transferase pi 1 (EC:2.5.1.18)

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KEGG pathway analysis of the genes common to the HSV-1 host/pathogen interactome and susceptibility genes in Alzheimer's disease from "Susceptibility genes are enriched in those of the herpes simplex virus 1/host interactome in psychiatric and neurological disorders." Pathogens and disease, 2013

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